Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum
Abstract
Human to vector transmission of malaria requires that some blood-stage parasites abandon asexual growth and convert into non-replicating sexual forms called gametocytes. The initial steps of gametocytogenesis remain largely uncharacterized. Here, we study this part of the malaria life cycle in Plasmodium falciparum using PfAP2-G, the master regulator of sexual conversion, as a marker of commitment. We demonstrate the existence of...
Paper Details
Title
Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum
Published Date
Nov 26, 2018
Journal
Volume
4
Issue
1
Pages
144 - 154
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