Original paper

‘Dendrimer-Cationized-Albumin’ encrusted polymeric nanoparticle improves BBB penetration and anticancer activity of doxorubicin

Volume: 555, Pages: 77 - 99
Published: Jan 1, 2019
Abstract
Glioblastoma is one of the most rapaciously growing cancer within the brain with an average lifespan of 12–15 months (5-year survival <3–4%). Doxorubicin (DOX) is clinically utilized as a first line drug in the treatment of Glioblastoma, however, its restricted entry into the brain via the blood–brain barrier (BBB), limited blood-tumor barrier (BTB) permeability, hemotoxicity, short mean half-life of 1–3 hr as well as rapid body clearance...
Paper Details
Title
‘Dendrimer-Cationized-Albumin’ encrusted polymeric nanoparticle improves BBB penetration and anticancer activity of doxorubicin
Published Date
Jan 1, 2019
Volume
555
Pages
77 - 99
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