Multi-functional core-shell Fe3O4@Au nanoparticles for cancer diagnosis and therapy
Abstract
Multi-functional core-shell Fe3O4@Au nanoparticles (Fe3O4@Au-DOX-mPEG/PEG-FA NPs) conjugated with doxorubicin (DOX), methoxy poly(ethylene glycol) (mPEG), and folic acid-linked poly(ethylene glycol) (PEG-FA) were synthesized for cancer theranostic applications. In the developed NPs, the DOX was chemically conjugated at the surface of core-shell Fe3O4@Au NPs using L-cysteine methyl ester (LCME) as a linker by acid-sensitive hydrazone bond. The...
Paper Details
Title
Multi-functional core-shell Fe3O4@Au nanoparticles for cancer diagnosis and therapy
Published Date
Feb 1, 2019
Volume
174
Pages
252 - 259
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