Cancer-associated stroma significantly contributes to the mesenchymal subtype signature of serous ovarian cancer

Volume: 152, Issue: 2, Pages: 368 - 374
Published: Feb 1, 2019
Abstract
Mesenchymal (MES) subtype of high-grade serous ovarian cancer (HGSOC) is associated with worse outcomes including survival and resectability compared with other molecular subtypes. Molecular subtypes have historically been derived from 'tumor', consisting of both cancer and stromal cells. We sought to determine the origins of multiple MES subtype gene signatures in HGSOC.Fifteen patients with MES subtype of HGSOC diagnosed between 2010 and 2013...
Paper Details
Title
Cancer-associated stroma significantly contributes to the mesenchymal subtype signature of serous ovarian cancer
Published Date
Feb 1, 2019
Volume
152
Issue
2
Pages
368 - 374
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