INTERACTIVE EFFECTS OF ALCOHOL CONSUMPTION AND APOE-E4 STATUS ON GENERAL COGNITIVE ABILITY IN MIDDLE-AGED MEN

Alcohol consumption is associated with cognitive decline and dementia in older adults. Presence of an ApoE-ε4 allele (ε4+) also increases risk for dementia. Researchers have also hypothesized that moderate alcohol consumption may be able to limit cognitive decline observed in older adults who are ε4+. To date, there is mixed support for an ApoE-by-alcohol consumption interaction in older adults. These relationships are understudied in...