Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru.

Published on Nov 14, 2018in BMC Research Notes
· DOI :10.1186/S13104-018-3919-Z
Miguel Angel Aguilar-Luis9
Estimated H-index: 9
(UPC: Universidad Peruana de Ciencias Aplicadas),
Fernando Palacios-Cuervo1
Estimated H-index: 1
(UPC: Universidad Peruana de Ciencias Aplicadas)
+ 9 AuthorsLuis J. del Valle27
Estimated H-index: 27
(UPC: Polytechnic University of Catalonia)
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Abstract
The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G–A2143G (28.6%).
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