Tumour heterogeneity and metastasis at single-cell resolution.
Abstract
Tumours comprise a heterogeneous collection of cells with distinct genetic and phenotypic properties that can differentially promote progression, metastasis and drug resistance. Emerging single-cell technologies provide a new opportunity to profile individual cells within tumours and investigate what roles they play in these processes. This Review discusses key technological considerations for single-cell studies in cancer, new findings using...
Paper Details
Title
Tumour heterogeneity and metastasis at single-cell resolution.
Published Date
Nov 26, 2018
Journal
Volume
20
Issue
12
Pages
1349 - 1360
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Notes
History