Rinsing Chronic Wounds with a Nitric Oxide Containing Solution – A Safe Treatment Approach to Support Wound Healing

Background: Nitric oxide (NO) is known for decades to play a crucial role in many physiological processes: this includes acting as an anti-microbial mediator/agent, vasodilator, inhibitor of platelet aggregation, immune modulator, and tissue regeneration via regulation of epidermal cell migration, collagen deposition and cytokine/chemokine microenvironment, making it a key player in wound healing. Methods: In order to demonstrate the therapeutic...