Review paper

The physiology of foamy phagocytes in multiple sclerosis

Volume: 6, Issue: 1
Published: Nov 19, 2018
Abstract
Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by massive infiltration of immune cells, demyelination, and axonal loss. Active MS lesions mainly consist of macrophages and microglia containing abundant intracellular myelin remnants. Initial studies showed that these foamy phagocytes primarily promote MS disease progression by internalizing myelin debris, presenting brain-derived autoantigens, and...
Paper Details
Title
The physiology of foamy phagocytes in multiple sclerosis
Published Date
Nov 19, 2018
Volume
6
Issue
1
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