Carnosine protects cardiac myocytes against lipid peroxidation products
Abstract
Endogenous histidyl dipeptides such as carnosine (β-alanine-l-histidine) form conjugates with lipid peroxidation products such as 4-hydroxy-trans-2-nonenal (HNE and acrolein), chelate metals, and protect against myocardial ischemic injury. Nevertheless, it is unclear whether these peptides protect against cardiac injury by directly reacting with lipid peroxidation products. Hence, to examine whether changes in the structure of carnosine could...
Paper Details
Title
Carnosine protects cardiac myocytes against lipid peroxidation products
Published Date
Nov 17, 2018
Journal
Volume
51
Issue
1
Pages
123 - 138
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