Ratiometric electrochemical sensing and biosensing based on multiple redox-active state COFDHTA-TTA

Here, a covalent organic framework with multiple redox-active state synthesized by amine-aldehyde condensation reaction between 4,4′,4′'-(1,3,5-triazine-2,4,6-triyl) trianiline and 2,5-dihydroxy terethaldehyde (COFDHTA-TTA) was used as novel electrochemical sensing and biosensing platform at first time. The COFDHTA-TTA was demonstrated to be two-dimensional nanosheets with highly ordered conjugated structure and uniform mesopores about 3.67 nm....