Nanotechnology

Organic chemistry

Combinatorial chemistry

Retrosynthetic analysis

Surface modification

Physical chemistry

Chemistry

Materials science

Natural product

Total synthesis

Chemical Society Reviews

In this review, recent examples featuring C-H functionalization in the synthesis of complex natural products are discussed. A focus is given to the way in which C-H functionalization can influence the logical process of retrosynthesis, and the review is organized by the type and method of C-H functionalization.

Recent applications of C–H functionalization in complex natural product synthesis