Early Events in the Endoplasmic Reticulum Unfolded Protein Response

Volume: 11, Issue: 4
Published: Apr 1, 2019
Abstract
The physiological consequences of the unfolded protein response (UPR) are mediated by changes in gene expression. Underlying them are rapid processes involving preexisting components. We review recent insights gained into the regulation of the endoplasmic reticulum (ER) Hsp70 chaperone BiP, whose incorporation into inactive oligomers and reversible AMPylation and de-AMPylation present a first line of response to fluctuating levels of unfolded...
Paper Details
Title
Early Events in the Endoplasmic Reticulum Unfolded Protein Response
Published Date
Apr 1, 2019
Volume
11
Issue
4
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