Galectin–Carbohydrate Interactions in Biomedicine and Biotechnology

Gal-1 and Gal-3 have been revealed as crucial targets for treating chronic inflammatory disorders, fibrotic diseases of varying etiologies, and cancer. The underlying biological processes are being carefully studied. Combined advanced enzymatic and chemical synthesis yield tailored nature-like and glycomimetic compounds for profiling the galectin ligand spectrum. Fast development of screening methods, X-ray crystallography, and molecular...