Metabolite profiling ofl -isocorypalmine in rat urine, plasma, and feces after oral administration using high performance liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry
Abstract
l ‐Isocorypalmine, an active alkaloid compound isolated from Rhizoma Corydalis yanhusuo , has been reported to possess biological activity for treating cocaine use disorder. A high‐performance liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry method was established for identification of the metabolites of l ‐isocorypalmine in urine, plasma and feces samples of rats after a single intragastric gavage of...
Paper Details
Title
Metabolite profiling ofl -isocorypalmine in rat urine, plasma, and feces after oral administration using high performance liquid chromatography coupled to Fourier transform ion cyclotron resonance mass spectrometry
Published Date
Nov 22, 2018
Volume
42
Issue
2
Pages
619 - 627
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