Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults
Abstract
Effects of Alzheimer's disease (AD) risk factors on brain volume changes may partly explain what happens during the preclinical AD stage in people who develop subsequent cognitive impairment (SI). We investigated predictors of neurodegeneration, measured by MRI-based volume loss, in older adults before diagnosis of cognitive impairment. There were 623 cognitively normal and 65 SI Baltimore Longitudinal Study of Aging participants (age 55–92...
Paper Details
Title
Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults
Published Date
Mar 1, 2019
Journal
Volume
75
Pages
178 - 186
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Notes
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