A Case of Pancreatitis with a Similar Course to Autoimmune Pancreatitis Occurring After Pembrolizumab Therapy in a Patient with Non-small Cell Lung Cancer

Volume: 58, Issue: 5, Pages: 344 - 348
Published: Oct 20, 2018
Abstract
背景.ペムブロリズマブの免疫関連有害事象で膵炎は稀とされており,これまでに本邦での報告例はない.症例.46歳,男性.肺腺癌cT3N0M1c,stage IVBと診断された.Tumor proportion score(TPS)が70%であり,1次治療としてペムブロリズマブを投与した.腫瘍縮小効果は見られたが,6コース目の投与後より上腹部痛が出現し,増悪したため救急外来を受診した.膵臓のソーセージ様のびまん性腫大と血中アミラーゼ,リパーゼの上昇を認め,ペムブロリズマブによる膵炎が疑われた.ペムブロリズマブの休薬とメチルプレドニゾロン60...
Paper Details
Title
A Case of Pancreatitis with a Similar Course to Autoimmune Pancreatitis Occurring After Pembrolizumab Therapy in a Patient with Non-small Cell Lung Cancer
Published Date
Oct 20, 2018
Volume
58
Issue
5
Pages
344 - 348
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