Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke

Volume: 84, Issue: 6, Pages: 934 - 939
Published: Nov 30, 2018
Abstract
We conducted a European-only and transancestral genome-wide association meta-analysis in 72,147 stroke patients and 823,869 controls using data from UK Biobank (UKB) and the MEGASTROKE consortium. We identified an exonic polymorphism in NOS3 (rs1799983, p.Glu298Asp; p = 2.2E-8, odds ratio [OR] = 1.05, 95% confidence interval [CI] = 1.04–1.07) and variants in an intron of COL4A1 (rs9521634; p = 3.8E-8, OR = 1.04, 95% CI = 1.03–1.06) and near...
Paper Details
Title
Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke
Published Date
Nov 30, 2018
Volume
84
Issue
6
Pages
934 - 939
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