3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs
Abstract
Three‐dimensional cell culture models, such as spheroids, can be used in the process of the development of new anticancer agents because they are able to closely mimic the main features of human solid tumors, namely their structural organization, cellular layered assembling, hypoxia, and nutrient gradients. These properties imprint to the spheroids an anticancer therapeutics resistance profile, which is similar to that displayed by human solid...
Paper Details
Title
3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs
Published Date
Oct 27, 2018
Volume
116
Issue
1
Pages
206 - 226
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History