The chromatin accessibility landscape of primary human cancers

Science56.90
Volume: 362, Issue: 6413
Published: Oct 26, 2018
Abstract
INTRODUCTION null Cancer is one of the leading causes of death worldwide. Although the 2% of the human genome that encodes proteins has been extensively studied, much remains to be learned about the noncoding genome and gene regulation in cancer. Genes are turned on and off in the proper cell types and cell states by transcription factor (TF) proteins acting on DNA regulatory elements that are scattered over the vast noncoding genome and exert...
Paper Details
Title
The chromatin accessibility landscape of primary human cancers
Published Date
Oct 26, 2018
Journal
Volume
362
Issue
6413
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