Use of Bone Health Agents (BHAs) in Patients with Metastatic Castration-resistant Prostate Cancer (mCRPC) Treated with Radium-223 after Abiraterone: An Interim Review of Reassure

When the radium-223 Phase III clinical trial (ALSYMPCA) was conducted, abiraterone was an investigational agent that was only available through clinical trials. REASSURE is a prospective, observational clinical study of radium-223 in patients with mCRPC with a 7-year follow-up (NCT02141438). Patients could have had anti-hormonal agents, such as abiraterone, prior to receiving radium-223. The objective of this interim review was to evaluate the...