Pathology

Antibody

Helminths

Intensive care medicine

Immunology

Strongyloides stercoralis

Disease

Strongyloidiasis

Strongyloides

Serology

Medicine

Journal of Microbiology Immunology and Infection

Strongyloidiasis is a major neglected tropical disease with the potential of causing lifelong infection and mortality. One of the ways for effective control of this disease is developing improved diagnostics, particularly using serological approaches. A serological test can achieve high diagnostic sensitivity and specificity, has the potential for point-of-care translation, and can be used as a screening tool for early detection. More research is needed to find clinically important antibody biomarkers for early disease detection, mapping, and epidemiological surveillance. This article summarizes human strongyloidiasis and the available diagnostic tools for the disease, focusing on describing the current antibody assays for strongyloidiasis. Finally, prospects of developing a more effective serodiagnostic tool for strongyloidiasis are discussed.

Serodiagnosis and early detection of Strongyloides stercoralis infection