Immune checkpoint inhibitors in cancer therapy
Abstract
In recent years immune checkpoint inhibitors have garnered attention as being one of the most promising types of immunotherapy on the horizon. There has been particular focus on the immune checkpoint molecules, cytotoxic Tlymphocyte antigen-4 (CTLA-4) and programmed cell death protein 1 (PD-1) which have been shown to have potent immunomodulatory effects through their function as negative regulators of T cell activation. CTLA-4, through...
Paper Details
Title
Immune checkpoint inhibitors in cancer therapy
Published Date
Jan 1, 2018
Volume
32
Issue
5
Pages
317 - 317
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