Therapeutic strategies targeting connexins

Volume: 17, Issue: 12, Pages: 905 - 921
Published: Oct 12, 2018
Abstract
The connexin family of channel-forming proteins is present in every tissue type in the human anatomy. Connexins are best known for forming clustered intercellular channels, structurally known as gap junctions, where they serve to exchange members of the metabolome between adjacent cells. In their single-membrane hemichannel form, connexins can act as conduits for the passage of small molecules in autocrine and paracrine signalling. Here, we...
Paper Details
Title
Therapeutic strategies targeting connexins
Published Date
Oct 12, 2018
Volume
17
Issue
12
Pages
905 - 921
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