Use of β-cyclodextrin inclusion concurrent with cationic surfactant shielding for the enhancement of ascorbic acid stability followed by ultra-high performance liquid chromatography and online preconcentration capillary electrophoresis

In the current study, β-cyclodextrin (β-CD) inclusion concurrent with cationic surfactant shielding was firstly evaluated for the successful stabilization of L-ascorbic acid (AA) under ambient lab conditions followed by ultra-high performance liquid chromatography (UHPLC) and online preconcentration capillary electrophoresis (CE). The combination of 0.44 mM β-CD with 10 mM cetyltrimethyl ammonium bromide (CTAB) cationic surfactant (β-CD-CTAB)...