Neurogenetic contributions to amyloid beta and tau spreading in the human cortex
Abstract
Tau and amyloid beta (Aβ) proteins accumulate along neuronal circuits in Alzheimer’s disease. Unraveling the genetic background for the regional vulnerability of these proteinopathies can help in understanding the mechanisms of pathology progression. To that end, we developed a novel graph theory approach and used it to investigate the intersection of longitudinal Aβ and tau positron emission tomography imaging of healthy adult individuals and...
Paper Details
Title
Neurogenetic contributions to amyloid beta and tau spreading in the human cortex
Published Date
Oct 29, 2018
Journal
Volume
24
Issue
12
Pages
1910 - 1918
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Notes
History