The application of transgenic and gene knockout mice in the study of gastric precancerous lesions

Volume: 214, Issue: 12, Pages: 1929 - 1939
Published: Dec 1, 2018
Abstract
Gastric intestinal metaplasia is a precursor for gastric dysplasia, which is in turn, a risk factor for gastric adenocarcinoma. Gastric metaplasia and dysplasia are known as gastric precancerous lesions (GPLs), which are essential stages in the progression from normal gastric mucosa to gastric cancer (GC) or gastric adenocarcinoma. Genetically-engineered mice have become essential tools in various aspects of GC research, including mechanistic...
Paper Details
Title
The application of transgenic and gene knockout mice in the study of gastric precancerous lesions
Published Date
Dec 1, 2018
Volume
214
Issue
12
Pages
1929 - 1939
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