Different Stability of DNA Origami Nanostructure between on Interface and in Bulk Solution

DNA origami possesses a promising prospect in the fields including cancer therapy, enhancing catalytic activity, controllable nanorobot, etc. However, all the brilliant performances are based on its structural integrity, which is a big challenge for this technology. In this paper, we investigated the effects of interface on the stability of DNA origami and found that with treatments like heating, pH fluctuation, reducing ionic strength, the...