The folate receptor β as a macrophage-mediated imaging and therapeutic target in rheumatoid arthritis

Volume: 9, Issue: 1, Pages: 366 - 378
Published: Feb 1, 2019
Abstract
Macrophages play a key role in the pathophysiology of rheumatoid arthritis (RA). Notably, positive correlations have been reported between synovial macrophage infiltration and disease activity as well as therapy outcome in RA patients. Hence, macrophages can serve as an important target for both imaging disease activity and drug delivery in RA. Folate receptor β (FRβ) is a glycosylphosphatidyl (GPI)-anchored plasma membrane protein being...
Paper Details
Title
The folate receptor β as a macrophage-mediated imaging and therapeutic target in rheumatoid arthritis
Published Date
Feb 1, 2019
Volume
9
Issue
1
Pages
366 - 378
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