Synthesis and Characterization of PDMS–PMOXA-Based Polymersomes Sensitive to MMP-9 for Application in Breast Cancer

Volume: 15, Issue: 11, Pages: 4884 - 4897
Published: Oct 1, 2018
Abstract
Cytotoxic compounds used to treat cancer are often associated with adverse events. The development of formulations activated by tumor-specific triggers would allow a reduction of systemic exposure while maintaining therapeutic concentrations in the tumor. One enzyme with proteolytic activity reported to be involved in tumor progression and assumed to be enhanced in the tumor environment is the matrix metalloproteinase 9 (MMP-9). In our study, we...
Paper Details
Title
Synthesis and Characterization of PDMS–PMOXA-Based Polymersomes Sensitive to MMP-9 for Application in Breast Cancer
Published Date
Oct 1, 2018
Volume
15
Issue
11
Pages
4884 - 4897
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