Gut microbiota–dependent modulation of innate immunity and lymph node remodeling affects cardiac allograft outcomes

Volume: 3, Issue: 19
Published: Oct 4, 2018
Abstract
We hypothesized that the gut microbiota influences survival of murine cardiac allografts through modulation of immunity. Antibiotic pretreated mice received vascularized cardiac allografts and fecal microbiota transfer (FMT), along with tacrolimus immunosuppression. FMT source samples were from normal, pregnant (immune suppressed), or spontaneously colitic (inflammation) mice. Bifidobacterium pseudolongum (B. pseudolongum) in pregnant FMT...
Paper Details
Title
Gut microbiota–dependent modulation of innate immunity and lymph node remodeling affects cardiac allograft outcomes
Published Date
Oct 4, 2018
Volume
3
Issue
19
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