Autism‐linked CHD gene expression patterns during development predict multi‐organ disease phenotypes

Recent large‐scale exome sequencing studies have identified mutations in several members of the CHD (Chromodomain Helicase DNA ‐binding protein) gene family in neurodevelopmental disorders. Mutations in the CHD 2 gene have been linked to developmental delay, intellectual disability, autism and seizures, CHD 8 mutations to autism and intellectual disability, whereas haploinsufficiency of CHD 7 is associated with executive dysfunction and...