Development of Silicone Hydrogel Antimicrobial Contact Lenses with Mel4 Peptide Coating

SIGNIFICANCE This study investigated the development of an antimicrobial coating on silicone hydrogel contact lenses that may have the capacity to reduce contact lens–related infection and inflammatory events. PURPOSE The purpose of this study was to develop an effective antimicrobial coating for silicone hydrogel contact lenses by attachment of Mel4 peptide. METHODS Lotrafilcon A, comfilcon A, somofilcon A, senofilcon A, and lotrafilcon B...