EGCG and enzymatic cross‐linking combined treatments for improving elastin stability and reducing calcification in bioprosthetic heart valves

Volume: 107, Issue: 5, Pages: 1551 - 1559
Published: Sep 29, 2018
Abstract
The failures of glutaraldehyde (GLUT) cross-linked bioprosthetic heart valves (BHVs) are mainly due to degeneration and calcification. In this study, we developed a new preparation strategy for BHVs named as “HPA/EDC/EGCG” that utilized 3,4-hydroxyphenylpropionic acid (HPA)-conjugated pericardium, epigallocatechin gallate (EGCG), and horseradish peroxidase (HRP)/hydrogen peroxide (H2O2) enzymatic cross-linking. HPA–pericardium conjugation was...
Paper Details
Title
EGCG and enzymatic cross‐linking combined treatments for improving elastin stability and reducing calcification in bioprosthetic heart valves
Published Date
Sep 29, 2018
Volume
107
Issue
5
Pages
1551 - 1559
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