Difference in immune infiltration in MSI and MSS BRAF mutant colorectal cancer.

e15624 Background: BRAFV600E mutation occurs in less than 10% of colorectal cancers (BmutCRCs) and is a strong predictor of poor prognosis not only in metastatic setting. Although BmutCRCs are usually considered a unique clinico-pathological entity, biological heterogeneity within this population has been recently described. Our aim was an extensive clinico-pathological study of a multicentric series of 74 BmutCRCs with a specific focus on the...