CEST-MRI for glioma pH quantification in mouse model: Validation by immunohistochemistry
Abstract
In glioma, the acidification of the extracellular tumor microenvironment drives proliferation, angiogenesis, immunosuppression, invasion and chemoresistance. Therefore, quantification of glioma extracellular pH (pHe) is of crucial importance. This study is focused on the application of the YbHPDO3A (ytterbium 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane) probe for in vivo glioma pHe quantification using chemical exchange saturation...
Paper Details
Title
CEST-MRI for glioma pH quantification in mouse model: Validation by immunohistochemistry
Published Date
Sep 5, 2018
Journal
Volume
31
Issue
11
Pages
e4005 - e4005
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