The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling

Volume: 17, Issue: 6
Published: Sep 14, 2018
Abstract
Calcium signaling is emerging as a key pathway controlling cellular senescence, a stable cell proliferation arrest playing a fundamental role in pathophysiological conditions, such as embryonic development, wound healing, cancer, and aging. However, how calcium signaling is regulated is still only partially understood. The inositol 1, 4, 5‐trisphosphate receptor type 2 (ITPR2), an endoplasmic reticulum calcium release channel, was recently shown...
Paper Details
Title
The nuclear receptor RXRA controls cellular senescence by regulating calcium signaling
Published Date
Sep 14, 2018
Journal
Volume
17
Issue
6
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