Altering polymerization temperature of antibiotic-laden cement can increase porosity and subsequent antibiotic elution

Volume: 42, Issue: 11, Pages: 2627 - 2632
Published: Sep 15, 2018
Abstract
To examine the role of polymerization temperature on the cement porosity and antibiotic elution to optimize antibiotic release from antibiotic-laden cement (ABLC). Elution profiles of vancomycin and tobramycin from ABLC discs prepared with low- and high-dose antibiotic dosages, cured at 8, 21, and 37 °C, and placed in phosphate buffered saline (PBS) at 37 °C were examined. Samples were collected at one, four, eight, 24, 72, 168, 336, and 1008...
Paper Details
Title
Altering polymerization temperature of antibiotic-laden cement can increase porosity and subsequent antibiotic elution
Published Date
Sep 15, 2018
Volume
42
Issue
11
Pages
2627 - 2632
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