Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer
Abstract
Cytokines are pivotal mediators of the immune response, and their coordinated expression protects host tissue from excessive damage and oxidant stress. Nevertheless, the development of lung pathology, including asthma, chronic obstructive pulmonary disease, and ozone-induced lung injury, is associated with oxidant stress; as evidence, there is a significant increase in levels of the modified guanine base 7,8-dihydro-8-oxoguanine (8-oxoG) in the...
Paper Details
Title
Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer
Published Date
Feb 1, 2019
Journal
Volume
194
Pages
59 - 72
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