Pharmacokinetics study of 16 representative components from Baoyuan Decoction in rat plasma by LC–MS/MS with a large-volume direct injection method
Abstract
Baoyuan decoction (BYD), a well-known traditional Chinese medicine (TCM) formula, is clinically used for the treatment of aplastic anemia, chronic renal failure, coronary heart disease, etc. The purpose of this study was to develop a large-volume direct injection liquid chromatography-mass spectrometry (LC–MS) method for simultaneous determination of 16 representative flavonoids and saponins in rat plasma after oral administration of BYD. The...
Paper Details
Title
Pharmacokinetics study of 16 representative components from Baoyuan Decoction in rat plasma by LC–MS/MS with a large-volume direct injection method
Published Date
Apr 1, 2019
Journal
Volume
57
Pages
148 - 157
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