DeepCEST: 9.4 T Chemical exchange saturation transfer MRI contrast predicted from 3 T data – a proof of concept study

Purpose To determine the feasibility of employing the prior knowledge of well‐separated chemical exchange saturation transfer (CEST) signals in the 9.4 T Z‐spectrum to separate overlapping CEST signals acquired at 3 T, using a deep learning approach trained with 3 T and 9.4 T CEST spectral data from brains of the same subjects. Methods Highly spectrally resolved Z‐spectra from the same volunteer were acquired by 3D‐snapshot CEST MRI at 3 T and...