Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging
Abstract
Nowadays, the freeze-drying of liposome dispersions is still necessary to provide a solid dosage form intended for different routes of administration (i.e., parenteral, oral, nasal and/or pulmonary). However, after decades of studies the optimization of process conditions remains still challenging since the freezing and the dehydration destabilize the vesicle organization with the concomitant drug leakage. Starting from the thermal properties of...
Paper Details
Title
Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging
Published Date
Aug 28, 2018
Journal
Volume
10
Issue
3
Pages
139 - 139
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