Epigenomics of mammary gland development
Abstract
Differentiation of stem cells into highly specialised cells requires gene expression changes brought about by remodelling of the chromatin architecture. During this lineage-commitment process, the majority of DNA needs to be packaged into inactive heterochromatin, allowing only a subset of regulatory elements to remain open and functionally required genes to be expressed. Epigenetic mechanisms such as DNA methylation, post-translational...
Paper Details
Title
Epigenomics of mammary gland development
Published Date
Sep 3, 2018
Journal
Volume
20
Issue
1
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Notes
History