Last ten years (2008-2018) of chiral ligand-exchange chromatography in HPLC: An updated review
Abstract
Chiral ligand-exchange chromatography is one of the elective strategies for the direct enantioresolution of small chelating compounds: amino acids, diamines, amino alcohols, diols, small peptides, etc. Unlike other methods, the interaction between chiral selector and analyte enantiomers is mediated by a cation, thus producing diastereomeric ternary complexes. Two main approaches are conventionally applied in chiral ligand-exchange...
Paper Details
Title
Last ten years (2008-2018) of chiral ligand-exchange chromatography in HPLC: An updated review
Published Date
Sep 12, 2018
Volume
42
Issue
1
Pages
21 - 37
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