Central suppressant therapies in unexplained chronic cough patients whose sputum cultures yielded Bjerkandera adusta.

Published on Jan 1, 2019in Allergology International4.806
· DOI :10.1016/J.ALIT.2018.07.009
Haruhiko Ogawa17
Estimated H-index: 17
,
Kazuya Tone5
Estimated H-index: 5
(Jikei University School of Medicine)
+ 1 AuthorsKoichi Makimura36
Estimated H-index: 36
(Teikyo University)
Source
Abstract
References8
Newest
#1Peter G. GibsonH-Index: 119
#2Gang Wang (Sichuan University)H-Index: 22
Last. Surinder S. Birring ('KCL': King's College London)H-Index: 53
view all 6 authors...
Background Unexplained chronic cough (UCC) causes significant impairments in quality of life. Effective assessment and treatment approaches are needed for UCC. Methods This systematic review of randomized controlled trials (RCTs) asked: What is the efficacy of treatment compared with usual care for cough severity, cough frequency, and cough-related quality of life in patients with UCC? Studies of adults and adolescents aged > 12 years with a chronic cough of > 8 weeks' duration that was unexplai...
125 CitationsSource
#1Emma Hilton (University of Manchester)H-Index: 17
#2Paul Marsden (University of Manchester)H-Index: 7
Last. Jaclyn A. Smith (University of Manchester)H-Index: 49
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Summary Background The urge-to-cough is a consciously perceived compulsion, previously investigated in healthy volunteers inhaling irritants. We aimed to characterise the urge-to-cough and associated sensations in a group of chronic cough patients attending a specialist clinic. Methods 100 patients with chronic cough [mean age 60 yrs (±11.89), 71 female, median cough duration 7 yrs (IQR 11.13) completed an investigator-led survey describing aggravating and relieving factors for urge-to-cough, as...
52 CitationsSource
#1Haruhiko OgawaH-Index: 17
#2Masaki FujimuraH-Index: 53
Last. Koichi Makimura (Teikyo University)H-Index: 36
view all 5 authors...
2 CitationsSource
#1Haruhiko OgawaH-Index: 17
#2Masaki FujimuraH-Index: 53
Last. Koichi Makimura (Teikyo University)H-Index: 36
view all 4 authors...
Among the various types of laryngeal paresthesia, the results of the study with use of a newly developed cough-related laryngeal sensation questionnaire suggested that a sensation of mucus in the throat (SMIT) can predict the presence of fungal colonization in chronic cough patients. Next to ‘cough’ or ‘sputum’, SMIT may become the third key clinical manifestation leading to successful prediction of the efficacy of antifungal therapy in chronic cough patients.
7 CitationsSource
#1Haruhiko OgawaH-Index: 17
#2Masaki Fujimura (Kanazawa University)H-Index: 53
Last. Koichi Makimura (Teikyo University)H-Index: 36
view all 4 authors...
Summary Background Recently we have reported 5 cases of allergic fungal cough (AFC), which is intractable and is characterized by sensitization to one of basidiomycetous fungus. Because AFC shows good clinical response to antifungal drugs, diagnosing AFC in patients with CIC may lead to the consequent management of CIC. Therefore, we determined the incidence of CIC among our hospital patients, and the frequency of BM fungi in sputum samples collected from patients with CIC. Furthermore we evalua...
30 CitationsSource
#1Haruhiko OgawaH-Index: 17
#2Masaki Fujimura (Kanazawa University)H-Index: 53
Last. Koichi Makimura (Teikyo University)H-Index: 36
view all 4 authors...
Objectives. This controlled study was performed to clarify the therapeutic benefit of itraconazole for the treatment of patients with chronic cough, wherein a sputum culture yielded basidiomycetous (BM) fungi. Methods. Of the 171 patients who visited our hospital for the diagnosis and treatment of chronic cough, BM was detected in the sputum of 39 patients. Informed consents were obtained from 21 patients who were subsequently enrolled in this trial. After the administration of the standard ther...
34 CitationsSource
#1Marc SautourH-Index: 16
#2Nathalie SixtH-Index: 8
Last. Alain Bonnin (University of Burgundy)H-Index: 27
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Abstract A one-year prospective survey of fungal air contamination was conducted in outdoor air and inside two haematological units of a French hospital. Air was sampled with a portable Air System Impactor. During this period of survey, the mean viable fungal load was 122.1 cfu/m 3 in outdoor air samples, and 4.1 and 3.9 cfu/m 3 in samples from adult and pediatric haematology units, respectively. In outdoor samples, Cladosporium was the dominant genus (55%) while in the clinical units, Penicilli...
101 CitationsSource
#1Surinder S. Birring (Glenfield Hospital)H-Index: 53
#2B PrudonH-Index: 5
Last. Ian D. PavordH-Index: 117
view all 6 authors...
Background: Chronic cough is a common condition which has a significant impact on quality of life. Assessment and management are hampered by the absence of well validated outcome measures. The development and validation of the Leicester Cough Questionnaire (LCQ), a self-completed health related quality of life measure of chronic cough, is presented. Methods: Patients with chronic cough were recruited from outpatient clinics. The development of the LCQ consisted of three phases: phase 1 (item gen...
555 CitationsSource
Cited By2
Newest
#1Haruhiko OgawaH-Index: 17
#2Kazuya ToneH-Index: 5
Last. Koichi MakimuraH-Index: 36
view all 3 authors...
Source
#1Suthida Piriyakarnsakul (Kanazawa University)H-Index: 1
#2K. Takarada (Kanazawa University)
Last. Masami Furuuchi (Kanazawa University)H-Index: 19
view all 6 authors...
AIMS: To provide information on the time-dependent behaviour of microbe staining by fluorescent dyes in the order of seconds, which is important in terms of the recent rapid and online techniques for microbe measurements and/or environmental microbe analysis. METHODS AND RESULTS: For combinations of yeast (Saccharomyces cerevisiae) and typical dyes, including DAPI (4',6-diamidino-2-phenylindole) and Auramine-O, a suspension of yeast cells in ultrapure water was injected into a dye solution in a ...
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