In situ synthesis of hydroxyapatite/carboxymethyl cellulose composites for bone regeneration applications

The study of inorganic hydroxyapatite (HA) assembly in polymer matrix is of great interest in bone tissue engineering field. An in situ synthesis method is employed in this study to synthesise carboxymethyl cellulose (CMC)/HA composite scaffolds to mimic the natural bone. The formation of HA in CMC matrix is initiated at three different temperature (30 °C, 60 °C and 90 °C) and the size of HA decreased with the increase of temperature. The...