Abstract A29: Effects of lysophosphatidic acid on ovarian cancer metastatic dissemination

Epithelial ovarian cancer (EOC) is typically detected after extensive intraperitoneal metastases, contributing to its status as the deadliest gynecologic malignancy. Metastasis occurs as tumor cells exfoliate from the primary tumor, permeate throughout the peritoneal cavity as single cells and multicellular aggregates (MCAs), adhering to the mesothelial layer of peritoneal tissues and subsequently inducing mesothelial retraction, submesothelial...