Mimicking nature: Fabrication of 3D anisotropic electrospun polycaprolactone scaffolds for cartilage tissue engineering applications

There is a growing need to develop strategies capable of engineering the anisotropic cartilaginous fibrous network in vitro and consequently overcome the anatomical and functional restrictions of the standard medical procedures used for cartilage regeneration. In this work, we suggest a fabrication procedure to build 3D anisotropic multi-layered fibrous scaffolds. Polycaprolactone (PCL) was used as bulk material for the different electrospun...