Characterization of UDP-Glycosyltransferase Involved in Biosynthesis of Ginsenosides Rg₁ and Rb₁ and Identification of Critical Conserved Amino Acid Residues for Its Function

Ginsenosides attract great attention for their bioactivities. However, their contents are low, and many UDP-glycosyltransferases (UGTs) that play crucial roles in the ginsenoside biosynthesis pathways have not been identified, which hinders the biosynthesis of ginsenosides. In this study, we reported that one UDP-glycosyltransferase, UGTPg71A29, from Panax ginseng could glycosylate C20-OH of Rh1 and transfer a glucose moiety to Rd, producing...