Organic chemistry

Combinatorial chemistry

Borylation

Chemistry

Alkyl

Aryl

Photochemistry

Journal of the American Chemical Society

An operationally simple deaminative borylation reaction of primary alkylamines has been developed. The formation of electron-donor-acceptor complexes between N-alkylpyridinium salts and bis(catecholato)diboron enables photoinduced single-electron transfer and fragmentation to carbon-centered radicals, which are subsequently borylated. The mild conditions allow a diverse range of readily available alkylamines to be efficiently converted into synthetically valuable alkylboronic esters under catalyst-free conditions.

Photoinduced Deaminative Borylation of Alkylamines